On the humorous side:

• My Brother, My Brother And Me - 3 brothers giving not-so-serious advice to listeners, reacting to questions from Yahoo Answers (when that was a thing), and overall being funny/silly
• My Dad Wrote A Porno - 3 people reacting to an “erotica” book series that one of the guys’ dad published (I would say the books are maybe only 5%-20% explicit, depending on the chapter) (some of the characters’ voices can be annoying/grating, and the narrator tends to repeat sentences after they react to them which can be annoying as well)
• No Such Thing As A Fish - the behind-the-scenes staff of the show QI bring up interesting facts and tidbits from history/nature/etc. (each episode is split into 4 parts where each member brings up a fact and the others react to it and bring up related facts)
• If I Were You - Jake & Amir from CollegeHumor giving advice to listeners (mostly in a sarcastic/tongue-in-cheek way but sometimes genuinely), mostly about relationships/dating
• SmartLess - Jason Bateman and Will Arnett (Arrested Development) and Sean Hayes (Will & Grace) interview a famous person each episode where only one of the hosts known who it is beforehand (it gets better after the first few episodes, though some conversations are less funny/entertaining than others)
• Office Ladies - Jenna and Angela from The Office (US) reacting to each episode of the show and bringing up behind-the-scenes stuff (some of episodes include interviews with other cast members/staff)

Not sure if they all fit entirely but:

• The Story Of Stuff (Annie Leonard)
• How The World Works (Noam Chomsky)
• Predictably Irrational: The Hidden Forces That Shape Our Decisions (Dan Ariely)
• The Hidden Brain (Shankar Vedantam) / Idiot Brain (Dean Burnett)
• The Myth Of Choice (Kent Greenfield) / The Paradox Of Choice (Barry Schwartz)
• The Free Will Delusion: How We Settled For The Illusion Of Morality (James B. Miles)
• Getting Free: Creating An Association Of Democratic Autonomous Neighborhoods (James Herod)
• The Best That Money Can’t Buy (Jacque Fresco)
• No Contest: The Case Against Competition (Alfie Kohn)