The Children of Time books by Adrian Tchaikovsky have a lot of those themes. Half of the first book is about an ark ship sent out to find a habitable planet because earth is dying. It spans hundreds of years as key crew members go in and out of hyper sleep. Relationships and political factions form and dissolve as the ageing ship continues its mission to find a new home.
The second book focuses on a terraforming crew that was sent to another star system to prepare a planet for humans. However, the planet’s ecology is so alien it proves very difficult to gain a foothold.
I loved the first two, but I had a hard time getting through the third. It has interesting concepts but it takes a long time to make its point. Plot structure spoilers:
Spoiler
The main reveal should have happened half way through, not at the end.
Apologies for mobile formatting