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Cake day: June 18th, 2023

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  • A protein is like a really long chain of simple monomers (amino acids), that you can think of as a long string of differently coloured beads. The ordering of the beads somewhat determines how the protein functions, but the major factor that determines it is how this long string is bundled up, i.e. “folded” (think of a ball of yarn).

    A DNA sequence tells us the sequence of the amino acids in a protein, but tells us nothing about how it is folded. It is of great interest to compute how a protein will fold, given its sequence, because then we can determine how and why it works like it does, and use gene-editing techniques to design proteins to do the stuff we want. This requires huge amounts of computational power, so you get the fold@home project :)

    Thanks for contributing!





  • Assuming

    • cylindrical human, 2m tall, 25 cm diameter.
    • air displaced from the point you teleport to is instantly moved to form a monolayer (1 molecule thick) on your surface.
    • The displacement of air is adiabatic (no heat is transferred, which will be true if the displacement is instantaneous)

    Volume of displaced air: ≈ 100L = 0.1m^3 At atmospheric conditions: ≈ 4 mol

    Surface area of cylindrical human: ≈ 1.58 m^2 Diameter of nitrogen molecule (which is roughly the same as for an oxygen molecule) : ≈ 3 Å Volume of monolayer: ≈ 4.7e-10 m^3

    Treating the air as an ideal gas (terrible approximation for this process) gives us a post-compression pressure of ≈ 45 PPa (you read that right: Peta-pascal) or 450 Gbar, and a temperature of roughly 650 000 K.

    These conditions are definitely in the range where fusion might be possible (see: solar conditions). So to the people saying you are only “trying to science”, I would say I agree with your initial assessment.

    I’m on my phone now, but I can run the numbers using something more accurate than ideal gas when I get my computer. However, this is so extreme that I don’t really think it will change anything.

    Edit: We’ll just look at how densely packed the monolayer is. Our cylindrical person has an area of 1.58 m^2, which, assuming an optimally packed monolayer gives us about 48 micro Å^2 per particle, or an average inter-particle distance of about 3.9 milli Å. For reference, that means the average distance between molecules is about 0.1 % of the diameter of the molecules (roughly 3 Å) I think we can safely say that fusion is a possible or even likely outcome of this procedure.






  • I definitely agree that breaking best practices in a way that could lead to UB or hard-to-find bugs should give point deduction. The sole requirement shouldn’t be “write standard compliant code”.

    However, a test does not simulate a real-world development environment, where you will have time to look through your code with fresh eyes the next day, and maybe even have someone review your code. The only thing a test reasonably simulates is your ability to solve the “thinking” part of the problem on your own. Thus, deducting points for trivial stuff that would 10/10 times be caught, either by the compiler, the developer or the reviewer, but isn’t “strictly correct” just seems pedantic to me.

    To be fair, other than the example by OP I have a hard time coming up with things that wouldn’t be either caught by the compiler or are very bad practice (which should give point deduction).



  • I have a masters degree in materials chemistry and engineering. When people find that out they often say stuff like “I could never understand that” or similar.

    I am of the firm belief that I could teach anyone everything I know given enough time and motivation. The thing is, I don’t think there’s anything special about me that makes me capable of doing what I do, other than thinking chemistry is extremely interesting. I don’t have a more capable brain or anything. I’m just a bit of a nerd.

    I absolutely agree that way too many people have the misconception that you have to be “special” to do a lot of the things many people find hard. It’s all about being interested enough to spend time learning it.